The S4’s pre-crash front seatbelts will tighten automatically in the event the vehicle detects an impending crash, improving protection against injury significantly. The Civic Type R doesn’t offer pre-crash pretensioners.
Both the S4 and Civic Type R have child safety locks to prevent children from opening the rear doors. The S4 has power child safety locks, allowing the driver to activate and deactivate them from the driver's seat and to know when they're engaged. The Civic Type R’s child locks have to be individually engaged at each rear door with a manual switch. The driver can’t know the status of the locks without opening the doors and checking them.
The S4’s standard pretensioning seatbelts also sense rear collisions and remove slack from the seatbelts to help protect the occupants from whiplash and other injuries. The Civic Type R doesn’t offer a whiplash protection system.
The S4 has a standard Secondary Collision Brake Assist, which automatically applies the brakes in the event of a crash to help prevent secondary collisions and prevent further injuries. The Civic Type R doesn’t offer a post collision braking system: in the event of a collision that triggers the airbags, more collisions are possible without the protection of airbags that may have already deployed.
The S4 has all-wheel drive to maximize traction under poor conditions, especially in ice and snow. The Civic Type R doesn’t offer all-wheel drive.
The S4 Premium Plus/Prestige has a standard Top View Cameras to allow the driver to see objects all around the vehicle on a screen. The Civic Type R only offers a rear monitor.
Both the S4 and Civic Type R offer rear cross-traffic warning, but the S4 with Rear Cross-Traffic Assist also has Automatic Brake Activation (automatically applies the brakes) to better prevent a collision when backing near traffic. The Civic Type R’s Cross Traffic Monitor doesn’t automatically brake.
The S4 has a standard Audi Connect CARE, which uses a global positioning satellite (GPS) receiver and a cellular system to help track down your vehicle if it’s stolen or send emergency personnel to the scene if any airbags deploy. The Civic Type R doesn’t offer a GPS response system, only a navigation computer with no live response for emergencies, so if you’re involved in an accident and you’re incapacitated help may not come as quickly.
Both the S4 and the Civic Type R have standard driver and passenger frontal airbags, front side-impact airbags, driver and front passenger knee airbags, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, plastic fuel tanks, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, rearview cameras and available blind spot warning systems.
The Audi S4 weighs 692 pounds more than the Honda Civic Type R. The NHTSA advises that heavier cars are much safer in collisions than their significantly lighter counterparts. Crosswinds also affect lighter cars more.

